Publications & Acknowledgments
Index
Movement Disorders
(Parkinson's disease, Huntington's disease, Dystonia)
Christopher H. Gibbons, MD, MMSc; Todd Levine, MD; Charles Adler,MD, PhD; Bailey Bellaire, BS; NingshanWang, PhD; Jade Stohl, BA; Pinky Agarwal, MD; Georgina M. Aldridge,MD, PhD; Alexandru Barboi, MD; Virgilio G. H. Evidente, MD; Douglas Galasko, MD; Michael D. Geschwind, MD, PhD; Alejandra Gonzalez-Duarte, MD; Ramon Gil, MD; Mark Gudesblatt, MD; Stuart H. Isaacson, MD; Horacio Kaufmann, MD; Pravin Khemani, MD; Rajeev Kumar, MD; Guillaume Lamotte,MD, MMSc; Andy J. Liu, MD, MS; Nikolaus R. McFarland, MD, PhD; Mitchell Miglis, MD; Adam Reynolds, MD; Gregory A. Sahagian, MD; Marie-Helene Saint-Hillaire,MD, PhD; Julie B. Schwartzbard, MD; Wolfgang Singer,MD, PhD; Michael J. Soileau, MD; Steven Vernino,MD, PhD; Oleg Yerstein, MD; Roy Freeman, MD, Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients
With Synucleinopathies
Stuart H. Isaacson, Gianpiera Ceresoli-Borroni, Alberto J. Espay, Rajesh Pahwa, Pinky Agarwal, Holly A. Shill, Jennifer Hui, Khashayar Dashtipour, Mark Lew, Peibing Qin, Andrea Formella, Mindy Grall, Peter A. LeWitt, Continuous Subcutaneous Apomorphine Infusion (CSAI) Responder Rates During Titration: Observations from the Open-label Phase 3 InfusON Trial
Andrew McGarry MD, Shane Rosanbalm PhD, Mika Leinonen MS, Prof C Warren Olanow MD, Dennis To PhD, Adam Bell PhD, Daniel Lee MS, Jamie Chang MD, Jordan Dubow MD, Prof Rohit Dhall MD, Daniel Burdick MD, Prof Sotirios Parashos MD, Jeanne Feuerstein MD, Prof Joseph Quinn MD, Prof Rajesh Pahwa MD, Mitra Afshari MD, Aldolfo Ramirez-Zamora MD, Prof Kelvin Chou MD, Arjun Tarakad MD, Corneliu Luca MD, Prof Karl Kieburtz MD, Safety, tolerability, and efficacy of NLY01 in early untreated Parkinson's disease: a randomised, double-blind, placebo-controlled trial
C. Warren Olanow, MD, FRCPC, FRCP (hon), Robert A. Hauser, MD, MBA, Daniel J. Burdick, MD, FAAN, Rohit Dhall, MD, MSPH, Joy Antonelle de Marcaida, MD, Ramon A. Gil, David L. Kreitzman, MD, Lawrence W. Elmer, MD, PhD, Andrew McGarry, MD, Karl Kieburtz, MD, and for the P2B Study Group, A Randomized Phase 3 Study Comparing P2B001 to its Components (Low-Dose Extended-Release Rasagiline and Pramipexole) and to Optimized Doses of Marketed Extended-Release Pramipexole in Early Parkinson's Disease
Peter LeWitt, Aaron Ellenbogen, Daniel Burdick, Steven Gunzler, Ramon Gil, Rohit Dhall, Ghazal Banisadr, Richard D'Souza, Improving levodopa delivery: IPX203, a novel extended-release carbidopa-levodopa formulation, Clinical Parkinsonism & Related Disorders, Volume 8, 2023, 100197, ISSN 2590-1125, https://doi.org/10.1016/j.prdoa.2023.100197
Camilleri M, Subramanian T, Pagan F, Isaacson S, Gil R, Hauser R, Feldman M, Goldstein M, Kumar R, Truong D, Chhabria N, Walter B, Eskenazi J, Riesenberg R, Burdick D, Tse W, Molho E, Robottom B, Bhatia P, Kadimi S, Klos K, Shprecher D, Marquez-Mendoza O, Hidalgo G, Grill S, Li G, Mandell H, Hughes M, Stephenson S, Vandersluis J, Pfeffer M, Duker A, Shivkumar V, Kinney W, MacDougall J, Zasloff M, and Barbut D. Oral ENT-01 targets enteric neurons to treat constipation in Parkinson disease: a randomized controlled trial. Annals of Internal Medicine. 2022 November 8; https://doi.org/10.7326/M22-1438
Lewitt PA, Hauser RA, Pahwa R, et al., and SPAN-PD Study Investigators including Burdick DJ. Safety and efficacy of CVT-301 (levodopa inhalation powder) on motor function during off periods in patients with Parkinson's disease: a randomized, double-blind, placebo-controlled phase 3 trial. Lancet Neurol. Feb 2019; 18(2):145-154. doi: 10.1016/S1474-4422(18)30405-8.
Agarwal P. (2019) Treatment of Orthostatic Tremor. In: Reich S., Factor S. (eds) Therapy of Movement Disorders. Current Clinical Neurology. Humana, Cham. doi: https://doi.org/10.1007/978-3-319-97897-0_39
Healio.com. Moving More in Old Age May Protect Memory, Thinking https://www.healio.com/internal-medicine/neurology/news/online/%7B36d9a452-f72f-40c5-8d3e-ea7b97bf77cf%7D/moving-more-in-old-age-may-protect-memory-thinking
Pahwa R, Tanner CM, Hauser RA, Isaacson SH, Nausieda PA, Truong DD, Agarwal P, Hull KL, Lyons KE, Johnson R, Stempien MJ. ADS-5102 (Amantadine) Extended-Release Capsules for Levodopa-Induced Dyskinesia in Parkinson Disease (EASE LID Study) A Randomized Clinical Trial. JAMA Neurol. Published online June 12, 2017. doi:10.1001/jamaneurol.2017.0943
Costa-Mallen P., Gatenby C., Friend S., Maravilla K.R., HuS.C., Cain K.C., Agarwal P., Anzai Y. (2017). Brain Iron Concentrations in Regions of Interest and Relation with Serum Iron Levels in Parkinson Disease. Journal of Neurological Sciences, In-Press.
doi: http://www.sciencedirect.com/science/article/pii/S0022510X17302691
Costa-Mallen P., Zabetian C.P., Hu S.C., Agarwal P., Yearout D., Checkoway H. (2016). Smoking and haptoglobin phenotype modulate serum ferritin and haptoglobin levels in Parkinson disease. J Neural Tranm. Published online June 27, 2016. DOI: 10.1007/s00702-016-1590-x.
Huntington Study Group FirstHD Investigators including Agarwal P. Effect of Deutetrabenazine on Chorea Among Patients with Huntington Disease: A Randomized Clinical Trial. JAMA. 2016;316(1):40-50. doi:10.1001/jama.2016.8655. http://jama.jamanetwork.com/article.aspx?articleid=2532012
LeDoux, M. S., Vemula, S. R., Xiao, J., Thompson, M. M., Perlmutter, J.S., Wright, L. J., ... Agarwal, P., on behalf of the Dystonia Coalition Investigators, Dystonia Genetic Consortium (2016). Clinical and genetic features of cervical dystonia in a large multicenter cohort. Neurology Genetics, 2(3), e69. http://dx.doi.org/10.1212/NXG.0000000000000069
Costa-Mallen P., Zabetian C.P., Agarwal P., Hu S.C., Yearout D., Samii A. … Checkoway H. (2015). Haptoglobin phenotype modifies serum iron levels and the effect of smoking on Parkinson disease risk. Parkinsonism Relat Disord, 21(9): 1087-92. http://www.prd-journal.com/article/S1353-8020(15)00291-6/pdf
Huntington Study Group Reach2HD Investigators including P. Agarwal. Safety, tolerability, and efficacy of PBT2 in Huntington's disease: a phase 2, randomized, double-blind, placebo-controlled trial. Published online November 14, 2014. www.thelancet.com/neurology
Agarwal, P., & Zehnder, R. J. (2014). Foot drop. In A. B. Ettinger & D. M. Weisbrot (Eds.), Neurologic differential diagnosis: a case-based approach (pp. 178-181). Cambridge: Cambridge University Press.
http://www.cambridge.org/us/academic/subjects/medicine/neurology-and-clinical-neuroscience/neurologic-differential-diagnosis-case-based-approach
Burdick D.J., Griffith A., Agarwal P. (2014). A case of tremor in klinefelter syndrome worsened by testosterone administration. Twenty Eighth Annual Symposium on Etiology, Pathogenesis, and Treatment of Parkinson Disease and Other Movement Disorders, 29(10), e2. http://onlinelibrary.wiley.com/doi/10.1002/mds.25967/citedby
Swanson, C. R., Li, K., Unger, T. L., Gallagher, M. D., Van Deerlin, V. M., Agarwal, P., … Chen-Plotkin, A. S. (2014), Lower plasma Apolipoprotein A1 levels are found in Parkinson's disease and associate with apolipoprotein A1 genotype. Mov. Disord.. doi: 10.1002/mds.26022
http://www.ncbi.nlm.nih.gov/pubmed/25227208
The Parkinson Study Group QE3 Investigators. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-552. doi:10.1001/jamaneurol.2014.131. http://archneur.jamanetwork.com/article.aspx?articleid=1851409
Sanders K and Burdick DJ. Huntington's Disease Case Study. Physician's Field Guide to Neuropsychology: Collaboration through Case Example, ch. 19. Springer Nature (2019): New York, NY.
Agarwal P, Ray S, Burdick D, Griffith A, and Madan A. Efficacy and safety of ADS-5102 (amantadine) extended-release capsules for treating levodopa-induced dyskinesia. Expert Opinion on Orphan Drugs. Published Online October 2018 at https://doi.org/10.1080/21678707.2018.1525532.
Kim HM, Leverenz JB, Burdick DJ, Srivatsal S, Pate J, Hu S-C, Millard SP, Davis MY, Samii A, and Zabetian CP. Diagnostic validation for participants in the Washington State Parkinson Disease Registry. Parkinson's Disease. Published online November 2018 at https://doi.org/10.1155/2018/3719578.
Madan A, Ray S, Burdick D, and Agarwal P. Management of lower urinary tract symptoms in Parkinson's disease in the neurology clinic. International Journal of Neuroscience. December 2017; 127(12): 1136-1149.
Burdick DJ, Griffith A, and Agarwal P. A case of tremor in Klinefelter syndrome worsened by testosterone administration. Parkinsonism and Related Disorders. April 2015; 21(4):419.
Burdick DJ, Cholerton B, Watson GS, Siderowf A, Trojanowski JQ, Weintraub D, Ritz B, Rhodes SL, Rausch R, Factor SA, Wood-Siverio C, Quinn JF, Chung KA, Srivatsal S, Edwards KL, Montine TJ, Zabetian CP, and Leverenz JB. People with Parkinson disease and normal MMSE score have a broad range of cognitive performance. Movement Disorders. Sept 2014; 29(10):1258-1264.
Burdick DJ and Leverenz JB. Parkinson's disease: pathology, anatomy, and behavior. Neuropsychiatric & Cognitive Changes in Parkinson's Disease & Related Movement Disorders, ch. 2. Cambridge University Press (2013): Cambridge, UK.
Burdick DJ, Griffith A, and Agarwal P. Mydriasis in a Parkinson Disease Patient on Low-Dose Carbidopa/Levodopa. Movement Disorders. March 2013; 28(3): 295.
Multiple Sclerosis
Jeffrey A Cohen, Samuel F Hunter, Theodore R Brown, Mark Gudesblatt, Ben W Thrower, Lily Llorens, Cindy J Souza-Prien, April E Ruby, David N Chernoff and Rajiv Patni (2018) Safety and efficacy of ADS-5102 (amantadine) extended release capsules to improve walking in multiple sclerosis: A randomized, placebo controlled, phase 2 trial.
https://journals.sagepub.com/doi/10.1177/1352458518754716
Brown T.R. & Simnad, V.I. (2017). A Topical Adhesive Containing Anesthetic and Heating Components to Reduce Injection Pain with Subcutaneous Multiple Sclerosis Medications. International Journal of MS Care: March/April 2017, Vol. 19, No. 2, pp. 85-90. doi: http://dx.doi.org/10.7224/1537-2073.2015-099
Brown T.R. & Simnad, V.I. (2016). Pilot Study of a Topical Adhesive Containing Anesthetic and Heating Components to Reduce Injection Pain with Subcutaneous Multiple Sclerosis Medications. International Journal of MS Care, In-Press. http://dx.doi.org/10.7224/1537-2073.2015-099
Brown T.R. & Simnad, V.I. (2016). A Randomized Crossover Trial of Dalfampridine Extended Release for Effect on Ambulatory Activity in People with Multiple Sclerosis. International Journal of MS Care: July/August 2016, 18(4), 170-176. http://ijmsc.org/doi/pdf/10.7224/1537-2073.2015-035
Brown T.R., Slee A. (2015). A randomized placebo-controlled trial of duloxetine for central pain in multiple sclerosis. International Journal of MS Care, 17(2), 83-89. http://ijmsc.org/doi/pdf/10.7224/1537-2073.2014-001
Brown T. R., Simnad V. I., & Slee A. E. (2013). A study of topical diclofenac for glatiramer acetate injection reactions. Fifth Cooperative Meeting of CMSC and ACTRIMS. International Journal of MS Care, 15(S3), 41. http://ijmsc.org/doi/pdf/10.7224/1537-2073-15.S3.1
Brown T. R., Slee A. E. (2013). A randomized, placebo-controlled study of duloxetine for pain in multiple sclerosis. Fifth Cooperative Meeting of CMSC and ACTRIMS. International Journal of MS Care, 15(S3), 47. http://ijmsc.org/doi/pdf/10.7224/1537-2073-15.S3.1
Mohr D. C., Lovera J., Brown T. R. , et al. A randomized trial of stress management for the prevention of new brain lesions in MS. Neurology. 2012 Jul 31;79(5):412-9. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405245/pdf/znl412.pdf
Brown TR, Simnad VI. Development and validation of a myometric test of strength in lower extremities for multiple sclerosis patients using handheld dynamometer. Consortium of MS Centers Annual Meeting. 2014 (oral presentation # RH01). Int J MS Care 2014 Volume 16, Supplement 3, 7.
Goodman AD, Brown TR, et al. A Pooled Analysis of Two Phase 3 Clinical Trials of Dalfampridine in Patients with Multiple Sclerosis. Int J MS Care 2014 16:153-60. http://www.ijmsc.org/doi/pdf/10.7224/1537-2073.2013-023
Cardiology
Michael R. Gold, Pier D. Lambiase, Mikhael F. El-Chami, Reinoud E. Knops, Johan D. Aasbo, Maria Grazia Bongiorni, Andrea M. Russo, Jean Claude Deharo, Martin C. Burke, Jay Dinerman, Craig S. Barr, Naushad Shaik, Nathan Carter, Thomas Stoltz, Kenneth M. Stein, Amy J. Brisben, Lucas V. Boersma and On behalf of the UNTOUCHED Investigators (including Kim, Edward). Primary Results from the Understanding Outcomes with the S-ICD in Primary Prevention Patients with Low Ejection Fraction (UNTOUCHED) Trial.
Liver Conditions
Enaksha Wickremsinhe, Antoniu Fantana, Erwin Berthier, Brook A Quist, Diego Lopez de Castilla, Charles Fix, Kahlil Chan, Jing Shi, Michael G Walker, Jennifer F Kherani, Holly Knoderer, Arie Regev, James J Harding, Standard Venipuncture vs a Capillary Blood Collection Device for the Prospective Determination of Abnormal Liver Chemistry, The Journal of Applied Laboratory Medicine, 2022;, jfac127, https://doi.org/10.1093/jalm/jfac127
Special Acknowledgments
MS Center
Ted Brown, MD, MPH
- Dr. Brown is interviewed for Real World Health Care's blog about pain management in patients with multiple sclerosis (MS).
2015 Herndon Award. Presented by the Consortium of Multiple Sclerosis Centers (CMSC), the Herndon Award for Outstanding IJMSC Article recognizes the best article published in the International Journal of MS Care during a given calendar year. Dr. Brown is the 2015 Herndon Award winner for his article "A Randomized Placebo-Controlled Trial of Duloxetine for Central Pain in Multiple Sclerosis," published in the March/April 2015 issue of IJMSC.
- Dr. Brown is featured on page 7 of the spring 2015 issue of the MS Connection newsletter.
